Lubricity is due to the long, repetitive bonds that create structures that trap a large volume of water inside the polymer. During play, waterlock functions similarly to PEO—as soon as the body absorbs the water trapped within the molecule's structure, both viscosity and lubricity decrease and drag increases. Rehydration or reapplication is necessary.

After a session, the polymer continues to extract water from the colon wall which leaves the fist chute thirsty and dry. Excess water and bulky foods must be consumed until all the waterlock is expelled during defecation. If a new session begins prior to its expulsion, a top will notice an incredibly dry colon.

Superabsorbent polymers are relatively nontoxic when swallowed or injected into the fist chute and there is relatively low toxicity following repeated exposure^{[ 2 ]}. Inhalation of the powder or exposure to the eyes can cause significant issues and should be avoided.

Aerobic bacteria (those that breathe oxygen) can digest sodium polyacrylate; therefore, discard unrefrigerated lube after a session. Colonization is slower than J Lube but keeping leftovers for more than a day is not worth the risk of infection.

Waterlock lubricants are safe for all toys and all gear.

Just add salt to Sodium Polyacrylate to disrupt the bonds. Laundry detergent works well on bedding exposed to waterlock.

A general best practice is to discard excess lube used in the play area immediately after a session. Lubes that have were stored in the fridge and not exposed to the play area can be kept for one week before degradation detrimentally affects lubricity.

Expiration dates for powder mixes are usually not specified; typically, you should discard powdered lube older than two years.

To prevent plumbing issues, do not rinse excess liquid or powder down the sink or toilet. Pour excess fluid into a puppy pad or disposable container and discard in the trash. If your off-the-shelf fisting lube has sodium polyacrylate as a minor ingredient (such as Elbow Grease), it can be washed down the drain without issue. Pure waterlock (sodium polyacrylate) can solidify in pipes which results in clogs.