Lipid molecules are hydrophobic, insoluble in water, and large in size. These characteristics help create a protective barrier that prevents injury to the fist chute's mucosal membrane. When used together with water-based lubes, this barrier decreases the loss of moisture to the absorptive tissues of the rectum and sigmoid colons.

When douching, applying a dab of semisolid shortening (Crisco, Trex, or Lard) to the walls of the anal canal decreases tissue damage caused by water expelled from the douche nozzle. This douching dab ensures you start your session free of trauma and swelling.

Physiologically, claims about increased LDSs are unfounded. Fats are too large to cross the intestinal lining and must be broken down into small units and bound to other molecules to pass into the bloodstream.

Individuals that have pancreatic and gall bladder disorders, such as people with cystic fibrosis, report fatty stools because fat is not absorbed without enzymes and proteins. This indicates the low probability of fat absorption in the fist chute (a place devoid of any fat digesting enzymes whatsoever). In fact, one study shows that CF patients have low cholesterol in general.

Finally, one scientific study indicates that fats that are solid at room temperature, such as butter, are poorly digested by the body. Altering these fats into fat droplets through frying causes them to be more readily absorbed. Fisting with lipids does not turn oils into droplets.

Lipids do not typically encourage or prohibit growth from most detrimental microorganisms that are common in our environments. In other words, they usually are not a food supply that allows rapid reproduction of bacteria and fungi that have been known to take over the digestive system.

Lower viscosity in semisolid and solid lipids may increase the spread of STIs that shed due to friction and drag (syphilis, HPV, etc.) To prevent cross contamination and re-contamination with these and other organisms, provide disposable single serve containers for each bottom.

Cleanup usually requires dish soap designed to remove grease. Sheets, towels, and pillows can be permanently stained by lipid-based lubes. TSP can remove oil stains, but it should be used infrequently due to its harsh nature to fabrics and mechanical components in HE washing machines.

Lipids will go rancid over time. A typical rule of thumb is to discard by the expiration date published on the container, or no more than one year after first opening the container.

Use individual containers during play to avoid double-dipping from the source container. Discard these containers in the waste bin after play. Do not pour oil down the drain. Recycling solid and semisolid lipid containers and or lipid packaging is not recommended. Recycling facilities prefer oil-free objects.

Crisco and generic shortening leave a residual odor in the air, on the skin, and on fabrics and furniture after fisting. While this odor has decreased in intensity with newer formulations, it has not been completely eliminated. To remove an odor from the environment, try:

• Opening the windows and using fans to increase air exchange.
• Washing tainted materials immediately with vinegar.
• Setting out a dozen baking soda boxes around the perimeter of your playroom to absorb the scent.